Post-Extubation Respiratory Support: Of Clinical Trials and Clinical Decisions

Analysis of Respiratory Behavior and Clinical Parameters for Successful Extubation in Premature Infants

Background The weaning process is complex and needs to be done carefully. The success of extubation in premature babies is associated with brain maturity and adequate function of the lungs. We aimed to identify the ventilator parameters and clinical conditions related to extubation success and failure in premature infants. Materials and Methods This is anobservational study, analytical and non-...

Evaluation of Clinical Trials

In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...

Making clinical decisions in cases with and without the support of clinical trials.

Support of clinical trials.

Evidence Based Medicine: Clinical Trials

Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...